血尿酸水平对急性冠脉综合征的预测价值

Predictor value of uric acid in acute coronary syndrome

目的:探讨血尿酸水平对急性冠脉综合征(ACS)的预测意义。方法:收集49例稳定性心绞痛(SAP),50例不稳定性心绞痛(UAP)及52例急性心肌梗死(AMI)病人的空腹血标本,测定尿酸(UA)、甘油三酯(TG)、总胆固醇(TC)、低密度总胆固醇(LDL-C)、空腹血糖(FBG)、肌酐(Cr)的含量,并进行对照比较。结果:3组间TG、TC、LDL-C、FBG及Cr水平无明显差异;UAP组及AMl组的尿酸水平接近,无统计学意义,但明显高于SAP组(P<0.05)。UAP组及AMI组的尿酸异常者比例相似,但也明显高于SA组(P<0.05)。结论:高尿酸血症是CHD的独立危险因子,能促进并预示ACS的发生。

Objective: To study the predictor value of uric acid (UA) in acute coronary syndrome. Methods: A total of 151 patients with coronary heart disease (CHD) were divided into three groups of stable angina (SAP, 52 cases), unstable angina (UAP, 50 cases) and acute myocardial infarction (AMI, 52 cases). The serum concentrations of UA, triglycerides (TG), total cholesterol (TO, low-density lipoprotein cholesterol (LDL-C). fasting blood glucose (FBG). and creatinine (Cr) were measured. Results: The serum uric acid levels of UAP and AMI patients were higher than those of SA P patients (P<0. 05 ), the levels of TG, TG, LDL-C, FBG, and Cr in three groups appeared no-difference. Conclusion: The level of serum uric acid may be the predictor factor in ACS.