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急性冠脉综合征患者血清β_2糖蛋白I抗体的测定及意义 被引量:4

Level of anti-β_2 glycoprotein I antibody and its clinical significance in patients with acute coronary syndromes
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摘要 目的:测定急性冠状动脉综合征(ACS)患者血清中β2糖蛋白I(β2-GPI)抗体水平并探讨其临床意义。方法:采用ELISA法测定34例ACS患者和30例对照者血清中β2-GPI抗体水平,并进行相关统计学处理。结果:ACS患者血清中β2-GPI抗体水平明显高于对照组[(21.89±6.83)U/ml:(14.96±11.13)U/ml,P<0.01]。结论:在ACS血栓形成的过程中,免疫因素的介入,β2-GPI抗体可能为ACS患者冠状动脉血栓形成过程中一个不容忽视的环节。 Objective: To investigate level of anti-β2 glycoprotein I antibody (anti-|VGPI) and its clinical significance in patients with acute coronary syndrome (ACS). Methods:Sera from 34 patients with ACS and from 30 controls were tested for the level of anti-β2-GPI antibody using an ELISA technique. Results: Anti-β2-GPI antibody levels in patients with ACS were significantly than those in control group [ (21. 89±.6.83) U/ml: (14.96±11.13) U/ml, P< 0. 01]. Conclusion: Anti-bbbbbbbbb2-GPI glycoprotein I antibody may be a significant factor in formation of coronary thrombus.
机构地区 安徽省立医院
出处 《心血管康复医学杂志》 CAS 2003年第1期24-25,共2页 Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词 β2糖蛋白I抗体 急性冠状动脉综合征 血栓 冠心病 Anti-β2 glycoprotein I antibody Acute coronary syndromes Thrombus
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  • 4[4]Zanon E, Prandoni P, Vianello F,et al.anti-2 glycoprotein I antibodies inpatients with acute venous thromboembolism:prevalence and association with recurrent thromboembolism[J].Thromb Res,1999,96(4):269-274.

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