高效液相色谱法测定复配添加剂中抗氧剂1010、1076和168的含量

Content determination of antioxidant 1010,1076 and 168 in compound additives by HPLC

采用Eclipse XDB-C_(18)色谱柱建立了复配添加剂中抗氧剂1010、1076和168含量的测定方法。抗氧剂的含量与其峰面积均呈现了良好的线性关系,相关系数r均大于0.9999。样品中抗氧剂1010、1076和168的平均回收率(n=9)分别为100.98%(RSD=0.85%)、99.34%(RSD=1.16%)、98.55%(RSD=1.24%)。该方法具有快速、准确、灵敏度高及方法稳定的特点,适用于复配添加剂中抗氧剂1010、1076、168含量的测定。

An Eclipse XDB-C18 chromatographic column was used to determine the content of antioxidant 1010,antioxidant 1076 and antioxidant 168 in compound additives.There was a good linear relationship between the antioxidant content and its peak area,and the correlation coefficient was greater than 0.9999.The average recovery(n=9)of antioxidant 1010,antioxidant 1076 and antioxidant 168 in the samples was 100.98%(RSD=0.85%),99.34%(RSD=1.16%)and 98.55%(RSD=1.24%),respectively.The method is rapid,accurate,sensitive and stable.It is suitable for the determination of antioxidant 1010,antioxidant 1076 and antioxidant 168 in compound additives.