摘要
DL-norgestrel is a widely used oral contraceptive. D-norgestrel (1) has been synthesized from an optically active intermediate (3) which was prepared from 13-ethyl-8, 14-seco steroid (2) by microbiological asymmetric reduction(1)Optically active compound (6) or (9) is also an intermediate for the synthesis of D-norgestrel. Thus, com-