SYNTHESIS OF 15 (R. S)-15-METHYL PROSTAGLANDIN E_2 METHYL ESTER AND ITS 11-METHYL ETHER DERIVATIVE BY 1,4-ADDITION OF AN ORGANOCOPPER REAGENT
SYNTHESIS OF 15 (R. S)-15-METHYL PROSTAGLANDIN E_2 METHYL ESTER AND ITS 11-METHYL ETHER DERIVATIVE BY 1,4-ADDITION OF AN ORGANOCOPPER REAGENT
摘要
The introduction of a 15-methyl group into a prostaglandin E2 （or its methyl ester） molecule blocks the metabolic action of the 15-hydroxyprostaglandin dehydrogenase and results in a considerable increase of the biological activities as well as prolongs the duration of the action of resulting derivative. Up to date, only one route for
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-
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-
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-
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-
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-
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-
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-
9李月明,张帆.环氧合酶-2在泌尿系肿瘤中的最新研究进展[J].临床误诊误治,2005,18(6):393-395. 被引量：2
-
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