摘要
Sister chromatid exchanges (SCE) can be detected and a clear demarcation between sister chromatids can be obtained by incorporating 5-bromo-2′-deoxyuridine (BrdU) into chromosomal DNA throughout two rounds of replication period and with the sister chromatid differential staining technique. Numerous experiments have proved that SCEs are very sensitive indicators of mutagens and carcinogens. This
