摘要
Ⅰ. INTRODUCTION In 1974, Collier et al. reported that morphine and its congeners inhibited the activity of adenylate cyclase （AC） of rat brain homogenates, stimulated by prostaglandins E1 （PGE1） and E, （PGE2）, and that the inhibition was mediated by opiate receptors. Sharma et al. also demonstrated that morphine and a series of opiates could inhibit this enzyme in neuroblastoma×glioma hybrid cells stimulated by PGE1,
