摘要
The metabolic pathway of glutamic acid (GLU) and γ-aminobutyric (GABA) has been widely studied in mammalian brain. In GABA metabolic pathway, GLU is precursor of GABA which was formed by L-glutamic decarboxylase (GAD) and cofactor pyridoxal phosphate and GABA was converted to GLU through α-ketoglutamic acid and GABA transaminase (GABA-T). GABA is a specific inhibitory transmitter,