A MICROCALORIMETRIC STUDY ON THE EFFECT OF INHIBITORS ON ENZYME——DETERMINATION OF INHIBITION CONSTANT K_i

In energy eonservatisn, release and transduction of ATPase are of vital importance. A microcalorimetric method was used to study the inhibitory effect of halogen compounds, e.g. ICH2COONa, BrCH2COONa, ICH2CONH2, on the activity of Mg2+ dependent soluble ATPase （F1） from pig heart mitochondria. It was found that the degree