摘要
Hemoglobin M (HbM) is one kind of abnormal hemoglobin which leads to the genetic methemoglobin disease. So far five hemoglobins M have been already reported. The hemoglobin M we studied in this note was found in Shanghai. It was confirmed that the hemoglobin was the HbMIwat (87 (FS) IIis→Tyr) by analyzing its amino acid sequence. The histidine in the position 87 of the a chain in this abnormal hemoglobin is replaced by tyrosine, the iron atom of heme is in ferric state and the hemoglobin becomes methe-
