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PHOTOCHEMISTRY OF HYPOCRELLIN A (Ⅰ) PHOTOOXIDATION OF HYPOCRELLIN A

PHOTOCHEMISTRY OF HYPOCRELLIN A (Ⅰ) PHOTOOXIDATION OF HYPOCRELLIN A
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摘要 A new effective phototherapeutic drug from Hypocrella bambusae (B. et Br.) Sacc., which is a kind of parasitic fungus growing in Yunnan Province, China, has been successfully used in the treatment of White Lesions of Vulva upon irradiation with a visible ray. The main constituent of Hypocrellab ambusae (B. et Br.). Sacc., Hypocrellin A (Ⅰ), which is a derivative of 4.9-dihydoxyperylene-3,10-quinone, was separated and identified by Wan Xiangyi et al. in 1980. When I is exposed under the sunlight in solution for a long period of time, Ⅰ can be completely photooxidized to its peroxide Ⅱ, which does not retain its phototherapeutic activity at all. The possible pathway towards its oxidation has been suggested to go through an intermediate stage
出处 《Chinese Science Bulletin》 SCIE EI CAS 1985年第1期75-79,共5页
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