摘要
5’-bromodeoxycytidine (BrdU)-resistance is a marker widely used in animal somatic cell genetics. The BrdU-resistance is the retardation of BrdU incorporation into DNA, which prevents the cell from phosphorating the thymidine or BrdU. BrdU-restance can be manifested by the change of osmolarity of cytoplasmic membrane or other unkown causes. It has been reported that even BrdU-resistant cells requiring
