摘要
In 1979 Verkleij et al. first reported the occurrence of lipidic particles on liposomcs. These lipidic particles may be associated with the nonbilayer lipid structure in biological membranes. In recent years, it has been proved by quite a few experiments that above the transition temperature, lipidic particles can be observed by using freeze-frac-ture electron microscopy when liposomes are prepared by PE either synthesized or
