TETRANDRINE:A NEW AND NATURAL INHIBITOR OF CALMODULIN-DEPENDENT Ca^(2+)-Mg^(2+)-ATPase IN ERYTHROCYTE MEMBRANE

Ca2+-Mg2+-ATPase is responsible for the active Ca2+-extrusion across the erythrocyte membrane and maintenance of low intracellular Ca2+ concentration. Ca2+-Mg2+-ATPase of erythrocyte has been shown to be regulated by calmodulin（CaM）, which is an ubiquitous Ca2+-binding protein and the major receptor