摘要
With the increasing use of monoclonal antibodies in immunoassay, an interesting effect has recently been observed in which the binding of one monoclonal antibody to an antigen increases the binding of a second monoclonal antibody. This effect has been termed enhancement and the first antibody, termed enhancing antibody. Two mechanisms have been proposed to explain the enhancement between monoclonal antibodies. The first is that the binding of an enhancing antibody