不同糖化血红蛋白控制水平的2型糖尿病患者血脂、血尿酸比较

Comparison of Blood Lipids and Uric Acid Level Between 2 Groups Type 2 Diabetes Patients with Different Control Levels of Glycosylated Hemoglobin

目的比较分析不同糖化血红蛋白(Hb Alc)控制水平的2型糖尿病患者间血脂、血尿酸水平情况。方法随机抽取门诊159名2型糖尿患者,通过分析他们6个月内最近1次早晨空腹采血生化报告,将他们分为控制不良组(Hb Alc≥7.0%)和控制良好组(Hb Alc<7%),分别对两组血糖、胆固醇、甘油三酯、高密度脂蛋白、低密度脂蛋白和血尿酸水平进行比较。结果控制不良组空腹血糖、胆固醇、甘油三酯和低密度脂蛋白水平均比控制良好组高,而高密度脂蛋白和血尿酸水平比控制良好组低。两组患者血糖、胆固醇、高密度脂蛋白、低密度脂蛋白水平差异有统计学意义(P<0.05)。结论 2型糖尿病患者Hb Alc控制不理想者的血糖、血脂代谢异常明显增加,需要严格控制Hb Alc水平。2型糖尿病患者Hb Alc控制好坏与血尿酸水平没有明显差异。

Objective To compare blood lipids and uric acid level between 2 groups type 2 diabetes patients with different control of glycosylated hemoglobin(Hb Alc). Methods Using simple random sample, 159 outpatients with type 2 diabetes were selected, which had been divided poor control group(Hb Alc≥7.0%) and good control group(Hb Alc<7%) according by their one recently morning fasting blood biochemical report within 6 months. And the levels of blood glucose, cholesterol, triglycerides, high density lipoprotein, low density lipoprotein, blood uric acid of 2 groups were compared. Results The levels of fasting blood glucose, cholesterol, triglycerides, low density lipoprotein(LDL) of the poor control group were higher than that of the good control group, while the levels of high density lipoprotein(HDL) and blood uric acid were lower than that of the good control group. There had statistics significance at difference of fasting blood glucose, cholesterol, HDL and LDL between two group(P<0.05). Conclusion The prevalence of blood sugar and blood lipid metabolic disorder are markedly increased in type 2 diabetes patients with poor Hb Alc-control, which need strict control Hb Alc, and it is no significant difference of blood uric acid level between two group patients with difference Hb Alc control levels.