CO_2激光吻合血管的实验研究

Small vascular anastomosis using CO_2 laser——an experimental study in cat

近年来美国和日本学者应用激光吻合血管获得了与传统缝合法相似或稍高的通畅率,并具有操作简便、缩短手术时间、损伤轻和并发症少等优点,引起了人们的重视。作者于1985年1月至1986年4月,从研制专门吻合血管的低功率 CO2激光器着手,采用自身对照法,一侧动脉采用新研制的CO2激光器吻合,对侧动脉则缝合吻合,观察和对比两者通畅率、超微结构、组织学和吻合口愈合强度的异同,证论该技术在临床应用的可能性。

In this experiment self-contrast was carried out.Fifty-four cats underwent the vascular anasto- mosis by using CO_2 laser in right brachial and femoral arteries,while on the left side a conve- ntional anastomosis was performed with 9-0 nylon suture.The vessels were harvested and studied by histology,seaning electron microscopy and measuring the maximal pressure intensity of vessel (MPIV)at the following intervals 2 hours,3 day,1,2,3 weeks.In both the groups the immediate patency rate was 100%.While the cumulative patency rate for CO_2 laser group was 96%,and 93.3% for the suture group.MPIV attained 296 mmHg in the immediate postoperative period of the laser group. The results of histological examination and scaning electron microscopy suggested that the CO_2 laser anastomosis has the following advantages over the suture:little trauma and inflammato- ry reaction;time-saving;smooth endothelial surface of the arteries and rapid healing.