摘要
异紫堇菲碱(Isocoredine)是罂粟科秃疮花[Dieranostigma leptopodum(Maxim)Fedde]植物中提取的生物碱。据文献报导,该生物碱具有镇痛、镇静和解痉等药理作用,同时可以改善冠脉循环和动脉血流量。我院1980年就提取了该生物碱。本文就我室提取的生物碱,观察了对整体动物体循环及其心率的影响,现报告如下。
The report concerns with the influence of the rapid haemodynamic effect on the heart ratet in animals.It was found that the rapid haemodynamic effect of isocoredine that was increased when a higher dosage was used while there was no influence in the lower dosage.In mice it increased the heart rate when the latter was slow but it decreased the heart rate when the higher heart rate is rapid.
出处
《解放军医学院学报》
CAS
1987年第2期154-155,共2页
Academic Journal of Chinese PLA Medical School
