新型隐球菌与格特隐球菌致病性及临床表现的比较综述

Comparison in pathogenicity and clinical manifestation between Cryptococcus neoformans and Cryptococcus gattii infections

新型隐球菌主要感染免疫抑制人群,常引起中枢神经系统感染,而格特隐球菌主要感染免疫力正常人群并以肺部感染为主。两者在致病性、临床表现及诊断治疗等方面均有所不同。本文对新型隐球菌与格特隐球菌在以上方面的差异作一综述。

Cryptococcus neoformans primarily infects immunocompromised individuals, and mainly causes central nervous system infection. While Cryptococcus gattii predominantly infects immunocompetent ones, and mainly leads to pulmonary infections. They differ in pathogenicity, clinical features, diagnosis and therapy. This review focuses on the comparison of aspects mentioned above between Cryptococcus neoformans and Cryptococcus gattii.