早期应用大黄在治疗严重多发性创伤胃肠功能障碍中的价值研究

Clinical value of early usage of rheum officinale in patients with gastrointestinal dysfunction induced by severe multiple trauma

目的研究早期使用大黄在治疗严重多发性创伤胃肠功能障碍中的价值。方法采用回顾性调查方法进行研究,对2014-2016年该院重症监护室(ICU)中的175例严重多发性创伤患者资料进行分析,按使用大黄的时间不同分为两组:早期使用大黄患者(早期组,85例),另一组为采用常规治疗患者(对照组,90例)。其中早期组患者入院后立即使用大黄,对照组出现胃肠功能障碍时再给予大黄治疗。比较两组胃排空能力、严重多发性创伤患者多器官功能障碍综合征(MODS)发生率、病死率、ICU住院时间。结果早期组胃排空能力高于对照组(P<0.05),MODS发生率、病死率以及住院天数显著低于对照组(P<0.05)。结论早期预防性使用大黄能够减少胃肠功能障碍的发生,降低并发症的发生,提高治疗质量,值得临床推广应用。

Objective To investigate the clinical value of early usage of rheum officinale in patients with gastrointestinal dysfunction induced by severe multiple trauma.Methods Data of a total of 175patients with severe multiple trauma from 2014-2016were retrospectively analyzed.The patients were divided into two groups:early usage of rheum officinale(early group,n=85)and conventional therapy(control group,n=90).Early group was given rheum officinale once they were hospitalized,while the control group was given rheum officinale when they had gastrointestinal dysfunction.Gastric emptying capacity,rate of multiple organ dysfunction syndromes(MODS),death rate and length of stay were compared.Results Gastric emptying capacity of early group was significantly higher than that of control group(P<0.05).And the rates of MODS,death rate and length of stay of early group was significantly lower than that of control group(P<0.05).Conclusion Early usage of rheum officinale could relieve gastrointestinal dysfunction,reduce complications,and improve the quality of treatment.It is worthy of promotion.