脂质水胶敷料联合自体富血小板凝胶治疗糖尿病足及慢性溃疡的效果

Effects of lipoid-colloid dressing with autologous platelet-rich gel treat on the patients with diabetic foot and chronic ulcer

目的通过脂质水胶敷料(URGO)联合自体富血小板凝胶(APG)治疗糖尿病足及慢性溃疡患者,观察其预后及费用情况。方法选取2015年6月至2017年6月于该院住院的45例糖尿病足及慢性溃疡患者作为研究对象,随机分为URGO组(21例)及URGO联合APG组(24例),观察两组患者出院时(入院时起第2、4周)及门诊随访(入院时起第6、8周)的创面愈合及治疗费用情况。结果两组患者溃疡愈合总有效率均为100.00%;但在不同治疗观察时期,URGO联合APG治疗组溃疡愈合时间短于URGO组,差异有统计学意义(P<0.05);URGO联合APG治疗组治疗费用少于URGO组,差异有统计学意义(P<0.05)。结论通过住院宣教、URGO联合APG治疗及门诊换药处理后糖尿病足及慢性溃疡患者取得了良好效果,能有效缩短糖尿病足及溃疡患者的创面愈合时间,减少治疗费用。

Objective To observe the prognosis and cost of patients with diabetic foot and chronic ulcer treated with lipoid-colloid dressing(URGO)combined with autologous platelet rich gel(APG).Methods A total of 45 patients with diabetic foot and chronic ulcer in the hospital from June 2015 to June 2017 were randomly divided into URGO group(21 cases)and URGO and APG group(24 cases).The wound healing and treatment costs of them in the hospital(2 weeks,4 weeks)and outpatient follow-up(6,8 weeks)were observed.Results The total effective rate of ulcer healing was 100.00%in the two groups.In different time points,the healing time of ulcers in group B was shorter than that in group A,and the difference was statistically significant(P<0.05).The cost of ulcer treatment in group B was less than that in group A,and the difference was statistically significant(P<0.05).Conclusion Through in-patient education,URGO combined with APG treatment and outpatient dressing change,the patients with diabetic foot and chronic ulcer have achieved good results,which can effectively reduce the wound healing time and treatment costs of patients with diabetic foot ulcer.