普通光镜尿棘形红细胞检查对血尿定位诊断的评价

The evaluation of acanthocytes analysis for the located diagnosis of hematuria with light microscope

目的评价用尿棘红细胞(G1细胞)计数鉴别肾小球性及非肾小球性血尿的价值。方法用普通光镜对130例血尿患者进行新鲜尿红细胞形态观察及G1细胞计数。结果(1)80例经肾穿刺确诊为肾小球病变的患者中,71例尿G1细胞计数≥5%,尿红细胞分类以非均一性红细胞为主者占90.5%,敏感性为88.8%。(2)50例非肾小球性血尿患者,G1细胞计数均【2%,尿红细胞分类以均一性红细胞为主者占82.7%,特异性为100%。结论普通光镜尿G1细胞计数结合红细胞形态分析,可用于血尿定位诊断与鉴别诊断。

Objective To evaluat the value differentiating glomerular hematuria from non-glomerular hematuria with urine acanthocyte counts. Methods We srveyed the erythrocytes as well as counted the acanthocytes in fresh urine from 130 patients suffered from hematuria with light microscope. Results There was an acanthocytes<5% in 71 of 80 patients suffered from glomerular disease, and in the 90.5% patients, most erythrocytes were anisocytes in their urine, and the susceptive rate was 88.8%. But in the 50 patients suffered from non-glomerular disease, the acanthocytes rate was<2%, and most erythrocyes were homogeneous in the urine of 82.7% patients, and the specificity rate was 100%. Conclusion The acanthocytes count and morphologic analysis of erythrocyte can be used to diagnose the hematuria locatedly and differentially with light microscope.