发热病人巨核细胞结构及功能的观察

The observation of the structure and function of the megakaryocyte of the fever patients

目的了解发热病人骨髓巨核细胞功能、巨核细胞核小体及多核巨核细胞变化。方法用显微镜观察含核小体巨核细胞和多核巨核细胞,分别求其百分率,检查同期外周血血小板,并分组比较。结果88例研究组病人含核小体巨核细胞检出率96.6%,对照组为43.3%。细菌性感染的巨核细胞核小体检出率11.31±8.25%五组研究组病人中最高,其次是病毒性感染组。研究组病人的多核巨核细胞检出率高达54.17%,而对照仅为16.7%,11例血小板减少者多核巨核细胞检出率达100%, 正常者仅40.50%。结论发热可导致巨核细胞结构和功能损害。

Objective To evaluate the change of the function of the megakaryocyte,the cell nucleosome of the megakaryocyte and the multi nuclear megakaryocyte in 88 fever cases as the study group.Methods To observe the structure of the megakaryocyte with microscopes and calculate the percentage respectively and the platelet of the same stage in peripheral blood.Based on the final clinical diagnosis,the study group of 88 cases was divided into five groups.Results The check-out ratio of the megakaryocyte containing the cell nucleosome and multin uclear was 96.6%,54.17%,respectively,while the contrast was only 43.3%,16.7%,respectively.The check-out ratio of the multinucle-ar megakaryocyte of the 11 fever cases with platelet be reduced was 100%,but the contrast was 40.5%.Conclusion Fever may be also result in the damage of the structure and function of the magakaryocyte.