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嘉兴地区拉米夫定治疗慢性乙型肝炎患者YMDD变异率分析

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摘要 拉米夫定是有效的抗乙型肝炎病毒(HBV)药物,已在临床广泛应用,但可因YMDD变异而耐药。对拉米夫定的耐药机制。
出处 《浙江检验医学》 2006年第2期6-7,共2页 Zhejiang Journal of Laboratory Medicine
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  • 1[1]Leung N W Y, Lai C L, Chang N T, et al. Extended lamivudine treatment in patients with chronic hepatitis B enhances hepatitis B e antigen seroconversion rates: results after 3 years of therapy[J]. Hepatology, 2001, 33(6): 1 527-1 532.
  • 2[2]Allen M I, Deslauriers M, Andrews C W, et al. Identification and characterization of mutations in hepatitis B virus resistant to lamivudine[J]. Hepatology, 1998, 27(6): 1 670-1 677.
  • 3[3]Santantonio T, Mazzola M, Iacovazzi T, et al. Long-term follow-up of patients with anti-HBe/HBV DNA-positive chronic hepatitis B treated for 12 months with lamivudine[J]. J Hepatol, 2000, 32(2): 300-306.
  • 4[4]Whalley S A, Brown D, Teo C G, et al. Monitoring the emergence of hepatitis B virus polymerase gene variants during lamivudine therapy using the LightCycler[J]. J Clin Microbiol, 2001, 39(4): 1 456-1 459.
  • 5[5]Paik Y H, Chung H Y, Ryu W S, et al. Emergence of YMDD motif mutant of hepatitis B virus during short-term lamivudine therapy in South Korea[J]. J Hepatol, 2001, 35(1): 92-98.
  • 6[6]Kobayashi S, Ide T, Sata M. Detection of YMDD motif mutations in some lamivudine-untreated asymptomatic hepatitis B virus carriers[J]. J Hepatol, 2001,34(4): 584-586.
  • 7Atkins M, Hunt CM, Brown N, et al. Clinical significance of YMDD mutant hepatitis B virus in a large cohort of lamivudine-treated hepatitis B patients (abstract). Hepatology, 1998, 28: 319A.
  • 8Leung NW, Lai CL, Chang TT, et al. Extended lamivudine treatment in patients with chronic hepatitis B enhances hepatitis Be antigen seroconversion rates: results after 3 years of therapy.Hepatology, 2001, 33: 1527-1532.
  • 9Nafa S, Ahmed S, Tavan D, et al. Early detection of viral resistance by determination of hepatitis B virus polymerase mutations in patients treated by lamivudine for chronic hepatitis B. Hepatology,2000, 32: 1078-1088.
  • 10Lok AS, Lai CL, Leung N, et al. Long-term safety of lamivudine treatment in patients with chronic hepatitis B. Gastroenterology,2003, 125: 1714-1722.

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