摘要
胰高血糖素样肽-1(GLP-1)可从多种途径实现降糖作用,近些年来已成为糖尿病研究领域的热点之一。中药治疗糖尿病历史悠久,现代药理学研究证实其具有多途径、多靶点的降糖作用机制。基于GLP-1降糖作用的中药干预研究也日益增多,现对中药干预GLP-1实现降糖作用的相关研究进行综述,以期为从GLP-1角度阐明中药的降糖作用机制及筛选研制新的降糖中药提供参考。
Glucagon-like peptide-1(GLP-1)can achieve glucose-regulating effects in a variety of ways and it has become one of the hotspots in the field of diabetes research in recent years.Traditional Chinese medicine has a long history of treating diabetes,and modern pharmacological studies have confirmed its multi-pathway and multi-target mechanism.The research on the glucose-regulating effects of traditional Chinese medicine based on GLP-1 is increasing.This article reviews the related researches so as to provide a reference for the clarification of glucose-regulating mechanism and screening of traditional Chinese medicine based on GLP-1.
作者
陈哲
楚淑芳
李惠林
赵恒侠
CHEN Zhe;CHU Shu-fang;LI Hui-lin;ZHAO Heng-xia(Institute of Clinical Pharmacology,Guangzhou University of Chinese Medicine,Guangzhou 510405,China;Shenzhen Traditional Chinese Medicine Hospital,Shenzhen 518033,China)
出处
《现代中药研究与实践》
CAS
2019年第4期79-82,共4页
Research and Practice on Chinese Medicines
基金
国家自然科学基金(81774225)
李惠林广东省名老中医药专家传承工作室(粤中医办函[2017]209号)
深圳市三名工程项目——张学文国医大师中医传承内分泌工作团队(SZSM201512043)
关键词
GLP-1
中药
糖尿病
综述
GLP-1
traditional Chinese medicine
diabetes
review
