应用网络STR生物信息对中国14个人群遗传距离的研究

The analysis on the genetic distances among fourteen populations in China using STR biological information online

目的 研究中国 14个族群间的遗传关系。方法 应用网络生物信息资源 ,收集CSF1PO ,TPOX和TH0 13个STR基因座的广州汉族、贵州汉族、西安汉族、景颇族、傣族、黎族、彝族、瑶族、壮族、回族、蒙古族和藏族的相关遗传资料 ,以及本研究组完成的新疆哈萨克族和锡伯族相应数据。通过亲缘系数 (I)和遗传距离 (D)分析 ,研究 14个人群间的遗传关系 ,并根据遗传距离绘制遗传树。结果 14个族群可被归为两个聚类群 :哈萨克族为一群 ,其他民族为另一群 ,属于蒙古人种。蒙古人种聚类群又可分为以下亚群 :傣族、壮族、彝族和黎族为一遗传距离相近的聚类亚群 ;3个汉族人群、藏族、云南回族、景颇族和瑶族为另一亚群 ,但两亚群间关系较密切。宁夏回族、新疆锡伯族与前两者有关 ,但距离较远。

Objective To study the genetic relationship among 14 populations. Methods The data of the three STR on other twelve populations (three Hans, two Hui, Li, Yi, Yao, Zhuang, Jingpo, Dai and Tibetan) were collected, and the genetic similarity coefficient and genetic distances among the fourteen populations were calculated, and the data of the three STR on Xibo and Kazak were reported by us. Phylogenetic trees based on the genetic distances were established. Results The results showed the fourteen populations were divided into two clusters. Kazak was involved in an identical cluster, and other thirteen populations in another. Conclusion Our result is consistent with historical data in the ethnic origin.