2-苄氧基苯酚的简易合成方法

Facile synthetic method for 2-benzyloxyphenol

目的制备 2 苄氧基苯酚。方法以邻苯二酚、苄基氯为原料 ,在碳酸钾在碘化钾催化下 ,通过调节酸碱度、用二氯甲烷萃取等操作制备 2 苄氧基苯酚。结果与结论未反应的原料、副产物与产物达到了较好的分离 ,直接得到固体 ,收率为 60 %。

Objective To prepare 2-benzyloxyphenol.Methods The 2-benzyloxyphenol was prepared from catechol by reacting with the benzyl chloride catalyzed by potassium iodide.In the presence of potassium carbonate by extracting with dichloromethane after adjusting the pH of the reaction mixture the reaction was carried out.Results and Conclusions The solid 2-benzyloxyphenol was gained in a solid state directly which was conveniently separated from the un-reacted starting material and by-product.The yield is up to 60%.