对甲苯磺酸催化合成对硝基苯甲酸乙酯的研究

Research on synthesis of p-nitro-ethylbenzoate with toluene-p-sulfonic acid as catalyst

以对甲苯磺酸为催化剂,合成了对硝基苯甲酸乙酯。对影响产率的诸因素进行了考察,其最佳反应条件为:醇酸摩尔比4∶1,催化剂用量为醇酸总量9%,反应时间2.5h,反应温度81℃～85℃,酯化反应产率高达95.8%。

pNitroethylbenzoate was synthesized with toluenepsulfonic acid as catalyst. Factors in fluencing yield were discussed. The optimum reaction conditions are alcohol/acid molar ratio 4∶1, catalyst amount(of alcohol and acid) 9%, reaction time 2.5 h,temperature 81 ℃～85 ℃. The yield under the optimum conditions was up to 95.8%.