急性胰腺炎并发胰性脑病26例分析

Pancreatic encephalopathy during acute pancreatitis (report of 26 cases)

目的 探讨急性胰腺炎并发胰性脑病的发病机理、诱发因素及防治措施。方法 回顾性分析 10年间收治的急性胰腺炎并发胰性脑病 2 6例的临床资料。结果 胰性脑病出现时常伴有高热、水和电解质代谢紊乱、低氧血症、氮质血症及血糖紊乱等因素存在。结论 胰酶对大脑损害是发生该病的病理基础 ,多种因素是发病的诱因 ,抑制胰酶释放是预防此病发生的关键措施 ,维持生理功能正常。

Objective To discuss the causes,agents and treatment of pancreatic encephalopathy in acute pancreatitis.Method We reviewed 26 cases of acute pancreatitis combined with pancreatic encephalopathy within recent 10 years.Results Pancreatic encephalopathy occurred always accompanied with such agents as hyperpyrexia, waterelectrolyte disturbance,hypoxemia, azotemia and bloodsugar disturbance etc.Conclusions The occurrence of the pancreatic encephalopathy is based on the harm that pancreatin does to the brain.The causes of pancreatic encephalopathy vary.To inhibit the releasing of pancreatin is the principle to prevent pancreatic encephalopathy, and to maintain normal physiological function,to control infection and nutritional support are the important links to prevent the pancreatic encephalopathy from happening.