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用介入方法获得的两个参数在评价左心室舒张功能中的应用 被引量:6

Evaluation of Left Ventricular Diastolic Function With Two ParametersObtained by Cardiointervention
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摘要 目的 :利用心脏介入技术测定部分冠心病患者的室腔硬度常数 (K)和等容舒张期压力下降时间常数 (T ) ,并与超声心动图指标进行比较 ,旨在了解介入方法评价左心室舒张功能的可行性与优越性。方法 :64例接受心导管检查的可疑心绞痛患者按其冠状动脉病变程度分为 :对照组 ( 10例 ) ,单支病变组 ( 2 6例 ) ,双支病变组 ( 12例 ) ,三支病变组 ( 16例 )。行左心室造影 ,连续同步记录心电图、左心室压力曲线和主动脉压力曲线。根据公式计算出K值和T值。所有研究对象术前接受常规超声心动图检查 ,记录舒张早期峰值速度 (E)、收缩晚期峰值速度(A)、E/A值并与T值比较。结果 :各病变组随着病变累及支数的增多T值和K值逐渐增加 ,A值也呈递增趋势 ,而E值和E/A值则呈递减趋势 ,与对照组相比均有显著差异 (P <0 0 5~ 0 0 1)。A值、E值、E/A值与T值的相关性良好。结论 :左心室舒张功能与冠状动脉病变程度密切相关。用介入方法获得的T值和K值可以较敏感、客观。 Objective: In order to examine the feasibility and the superiority of cardiointer ventional method in left ventricular diastolic function (LVDF) evaluation, we calculated two parameters obtained by cardiointervention:the pressure descending time constant (T) and the ventricular stiffness constant (K) of some patients with coronary heart disease (CHD), and compared T with the indices obtained from echocardiography Methods: Sixty four patients suspected to have angina pectoris and undergoing cardiointerventional examination took part in our experiment The patients were divided into 4 groups: control ( n =10), single branch lesion ( n =26), double branch lesion ( n =12), three branch lesion( n =16) Left ventriculography was made for all patients The electrocardiogram, pressure curve of left ventricle (LV) and aorta were recorded simultaneously K and T were calculated according to the formulas P=a+b·e KV and LnP=t/T+B respectively All the patients received echocardiography before the procedure E peak, A peak and E/A were recorded and compared with T.Results: As the number of diseased arteries increased, T and K rose A peak also showed a tendency to rise, while E peak and E/A decreased Unpaired T test showed significant difference between control group and the groups with lesions According to the result of correlation analysis, T appeared to be closely correlated with A peak, E peak and E/A Conclusion: T and K obtained through cardiointerventon were sensitive and objective in LVDF evaluation
出处 《中国循环杂志》 CSCD 北大核心 2003年第1期22-24,共3页 Chinese Circulation Journal
基金 沈阳市科委资助项目沈科发 [1 999] 70
关键词 介入方法 左心室舒张功能 室腔硬度常数 压力下降时间常数 等容舒张期 Ventricular function, left Ventricular stiffness constant Pressure descending time constant
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