贞芪扶正胶囊配合化疗治疗中晚期肿瘤76例

Chemotherapy Combined with Zhenqifuzheng Capsules in the Treatment of Cancer (76 Cases)

目的 :观察贞芪扶正胶囊对化疗疗效的影响及对化疗所致骨髓抑制的防治作用。方法 :随机将 76例中晚期肿瘤患者分为两组。治疗组 38例 ,在常规化疗同时 ,加贞芪扶正胶囊 4粒 ,tid ,口服 ,连续 4周 ;对照组 38例 ,为单用化疗治疗的同种病例。观察临床疗效及第 1周、第 2周、第 3～ 4周外周血白细胞计数、血红蛋白含量及血小板计数的变化。结果 :治疗组总缓解率 (42 .2 % )高于对照组 (36 .8% ) ,但差异无显著性 ;外周血白细胞计数在第 1周、第 2周、第 3～ 4周治疗组明显高于对照组 (P <0 .0 5) ,血红蛋白和血小板也有不同程度提高 ,但差异无显著性 (P >0 .0 5)。结论 :贞芪扶正胶囊配合化疗短期内对提高化疗的总缓解率帮助不大 ,但对防治化疗所致骨髓抑制 。

Objective:To explore the clinical prognosis and marrow inhibition by chemotherapy combined with zhenqifuzheng capsules in the treatment of cancer. Methods:76 patients were randomly divided into 2 groups. The obvervation group (38 cases) were treated with chemotherapy combined with zhenqifuzheng capsules 4 caps, po, tid, for 4 weeks. The control group(38cases) were treated with chemotherapy only. Observing the prognosis and the counting of white blood cells, hemoglobin and blood platelets from the first to fourth week. Results:The remission rate was higher in the observation group(42.2 %) than that in the control group (36.8 %), but no significant difference increased( P >0.05). There was a higher white blood cell count as compared with the control group, at first week, second week and third to fourth week( P <0.05), whereas there was no significant difference in the counting of hemoglobin and blood platelets( P >0.05). Conclusion:No beneficial effect of zhenqifuzheng capsules was evident in terms of remission. However it markedly inhibited the decrease of white blood cells.