转移生长因子-β在早期胚胎组织的表达

The study of TransformGrowth Factor-β in the Development of Human Embryo

目的 研究转移生长因子 β(TransformGrowthFactor,TGF β)在胚胎的肝、脑室、和脊髓等组织器官中增殖和分化中的作用。方法 用 5 1天的人胚胎行免疫细胞化学ABC法染色。结果 在胚胎第 5 1天 ,肝、脑室、和脊髓等组织器官中均有TGF β阳性细胞存在 ,不同器官其阳性细胞的数量、反应强弱和表达情况有差异。结论TGF B在人胚胎发育过程中 ,对肝。

Objective We investigate the expression and the distribution of the transformgrowth factor-βin the liver ,lung and spinal cord of human embryo. Methods The human embryo in 51 days and immunocytochemistry ABC technique with anti-TGF-βantibody were used. Result There wereTGF-βimmuno-positive substancein thecytoplasm and nuclei of neuroepithlium in the liver ,lung and spinal cord. There were differential expression on TGF-βimmuno-positive substance in differential cells and differential organs .ConclusionThese results might suggest that TGF-β play an important role in promoting and maintaining the biological function in the development of human embryo