早产因素1∶3配比病例—对照研究

CASE CONTROL STUDY FOR RISK FACTORS OF PREMATURE BIRTH

早产(PB)发生率各地报道不尽相同,一般为3～16.8%,约占妊娠总数的十分之一,是围产期发病和死亡的首要原因,而且四分之一的早产儿留有神经或智力方面的后遗症。

In order to investigate the risk factors of premature birth, a matched case-control study with 163 premature birth mother matched 489 controls was conducted, Inlormation was from first affiliated hospital, Sun YatSen University of Medical Science, Guangzhou, China. Data were analysed with condition logistic regression model. Twin pregnancy, premature birth history and premature rupture of fetal membranes as well as placcnto previa are the major risk factors of the premature birth. statistically, tne relative risk were 23.45 (95%Cl 4.917-111.8, P<0.00l). 9.67(95% Cl 2.133-43.77, P=0.003), 7.11 (95%Cl 450-12.049, P<0.001), and 4.72 (95%CL 1.353-1.644. P=0.015). Occipitotransverse position is a protective factor for premature birth, the relative risk was 0.10 (95%CL 0.012-0,829. p=0.033). the cause was unknown remains to be further studied.