门脉高压性胃病发生相关因素的临床研究

Study of correlation factors of portal hypertense gastropathy occurence

[目的 ]探讨门脉高压性胃病 (portalhypertensegastropathy ,PHG)发生与幽门螺旋杆菌 (heli cobacterphlori,HP)感染、食道胃底静脉曲张程度及门静脉宽度的相关性。 [方法 ]分析了 174例肝硬化患者及 75 2例慢性胃炎患者的胃镜及超声资料。 [结果 ]①PHG在肝硬化门脉高压患者的发生率为 5 2 % ,PHG引起的出血占肝硬化上消化道出血的 33% ;②伴与不伴PHG肝硬化患者HP感染率分别为 33 3%、4 3 1% ,两组比较无差异 (P >0 .1) ,非肝硬化的慢性胃炎患者HP感染率显著高于肝硬化组 ,为 76 7% (P <0 .0 5 ) ;③轻度PHG组 ,食道静脉曲张均为中度 ;重度PHG组 ,食道静脉曲张中度占 8% ,重度占 79%。两组比较 ,门静脉宽度无显著性差异 (P >0 .1)。 [结论 ]PHG的发生与食道胃底静脉曲张程度成正相关 ,与HP感染及门静脉宽度无关。

To study the relationship between the occurrence of portal hypertense gastropathy (PHG) and Helicobacter pylori (HP) infection and esophageal varices. To analyse the incidences of HP infection and the aggravation of esophageal varices and the width of oprtal vein in 174 cirrhosis patients and 752 chronic gastritis patients. ①The incidences of PHG in upper gastrointestinal bleeding of cirrhosis was 33%. ②The incidences of HP infection in the cirrhosis patients with and without PHG were 33.3%?43.1%, no statistrical difference ( P >0.1),but in chronic gastritis without cirrhosis patients was significantly higher than the group of PHG, was 76.7% ( P >0.5). ③The progress of PHG followed the aggravation of esophageal varices, the width of portal vein were no statistics difference in light PHG and the severe PHG ( P >0.1).[Conclusions] The occurence of PHG is positive relate to aggravation of esophageal varices, and not related to HP infection and the width of portal vein.