前列泰颗粒对慢性前列腺炎的抗炎作用研究

Anti - inflammatory Effect of Qianlie Tai Granule on Chronic Prostatitis

目的 观察前列泰颗粒治疗慢性前列腺炎的抗炎作用。方法 以大鼠无菌性慢性前列腺炎模型和小鼠急性炎症、大鼠慢性炎症模型研究前列泰颗粒的药效作用。结果 前列泰颗粒能降低无菌性慢性前列腺炎大鼠的血白细胞,抑制组织重量增加,对前列腺组织发生的慢性炎性病理改变有显著改善作用。前列泰颗粒对2％复合巴豆油所致的早期渗出性耳肿胀有明显抑制作用,对2％琼脂所致的晚期增生性肉芽肿形成也有明显抑制作用。结论 前列泰颗粒有明显的抗前列腺炎作用,有抑制早期炎症和晚期炎症的作用。

Objective To observed the and - inflammatory effect of Qianlie Tai Granule (QTG) on chronic prostatitis. Methods Three models, asepsis and chronic aseptic prostatitis rat model, acute inflammation mouse model and chronic inflammation rat model, were adopted to observe the pharmacocynamic action of QTG. Results QTG decreased the number of WBC, inhibited the increasing of prostate tissue weight and improve the inflammatory lesion in prostate tissue of chronic aseptic inflammation rats. QTG also had an obvious inhibitory effect on early exudative auricular swelling induced by 2% compound croton oil and late proliferative granuloma induced by 2% agar. Conclusion QTG has an obvious effect for prostatitis. It can inhibit the early and late inflammation .