盐酸洛美沙星中空栓剂治疗细菌性阴道病68例

Treatment of Bacterial Vaginosis with Hollow Pessary of Lomefloxacin Hydrochloride

目的 :观察盐酸洛美沙星中空栓剂对细菌性阴道病 (BV)的临床疗效。方法 :将 10 2例BV患者随机分成两组 :对照组 3 4例 ,每日 1枚甲硝唑栓剂 (0 .3g) ;治疗组 68例 ,每日 1枚盐酸洛美沙星中空栓剂 (0 .3g) ,并于疗程第 3 ,4,5 ,7天考察治疗效果。结果 :治疗组治愈 68例 ,治愈率 10 0 .0 % ,平均疗程 3 .4d ;对照组治愈 3 0例 ,未愈 4例 ,治愈率88.2 % ,平均疗程 6.7d。两组治愈率比较差异有显著性 (P <0 .0 5 ) ,平均疗程差异有极显著性 (P <0 .0 1)。结论

Objective:To survey the clinical therapeutic effectiveness of hollow pessaries (HP) of lomefloxacin hydrochloride in the treatment of bacterial vaginosis (BV). Methods:102 patients with BV were randomly divided into two groups. Patients of the control group( n =34) were given each daily one pessary of tinidazole (0.3 g), while those of the treatment group( n =68) were given each daily one HP of lomefloxacin hydrochloride(0.3 g). The therapeutic effectiveness was kept under observation on the 3 rd , 4 th , 5 th and 7 th days of treatment. Results:The total cure rates were 100% (68/68) in the treatment group and 88.2%(30/34) in the control group, respectively( P <0.05). The average time of medication necessitated by patients of the treatment group(3.4 d)was significantly shorter than that of the control group(6.7 d)( P <0.01). Conclusion:HP of lomefloxacin hydrochloride was found to have a good effect in the treatment of BV.