摘要
目的 :探讨超大剂量氨甲喋呤 (MethotrexateMTX)保守治疗异位妊娠的临床价值。方法 :6 0例患者分大剂量MTX 1.0mg/(kg·d)qod× 4静滴 ,次日甲酰四氢叶酸钙 (CF) 0 .1mg/(kg·d)qod× 4肌注解毒 (A组 ) ,超大剂量MTX 1.5mg/(kg·d) qod× 4静滴 ,CF 0 .15mg/(kg·d) qod× 4肌注 (B组 )进行比较。结果 :B组较A组能明显缩短血 β hCG(绒毛膜促性腺激素 )降至正常范围的时间 ,减少住院天数 ,提高治疗成功率 (P <0 .0 5)。结论 :超大剂量氨甲喋呤治疗异位妊娠有一定临床应用价值。
Objective :To evaluate the treatment of ectopic pregnancy with overdosage of methotrexate .Methods :60 cases were divided into two groups . Patients in Group A were treated with 1.0mg/ (kg·d) qod × 4 of methotrexate ivdrop and nextday with 0.1mg/(kg·d) qod×4 of CF inject,compared with group B who received 1.5mg/(kg·d) qod×4 of methotrexate ivdrop and nextday with 0.15mg/(kg·d) qod×4 of CF inject.Results:Group B shows great differences in shortening the time of blood β hCG restoring to level, decreasing days in hospital,and raising cure rate than that of group A (P<0.05).Conclusion:Overdosage of methotrexate is an effective treatment for ectopic pregnancy.
出处
《右江医学》
2003年第1期45-46,共2页
Chinese Youjiang Medical Journal
