摘要
测定20例心力衰竭患儿血清脂质过氧化物(LPO)含量,结果显示,心衰患儿血清LPO含量(4.64±2.19μmol/L)显著高于正常组(2.77±0.56μmol/L)及心脏病无心衰组(2.84±0.88μmol/L),Ⅲ°心衰组(5.80±2.89μmol/L)高于Ⅱ°心衰组(3.54±0.66μmol/L).提示氧自由基引发的脂质过氧化损伤在心力衰竭发生、发展的病理过程中起一定作用.
Serum lipid peroxides(LPO)were measured in twenty children with heart failure.The mean value of LPO was 4.64±2.19μmol/L in the heart failure group, which was significantly higher than that of the normal group(2.77±0.55μmol/L)and that of the heart diseases without heart failure group(2.84±0.88μmol/L).The mean value of the Ⅲ degree heart failure group(5.80±2.89μmol/L)was higher than that of the Ⅱ degree heart failure group (3.54±0.66μmol/L).These results suggest.that oxygen free radicals may play a role in the pathological process of heart failure.
基金
国家自然科学基金
关键词
心力衰竭
氧自由基
过氧化脂质
heart failure
oxygen free radical
lipid peroxide
