豚鼠、大鼠、猫离体肠道运动及推进行为的比较生理学特点

Characters of Comparative Physiology on Motility and Propulsive Behaviour of Isolated Intestinal Segments from Cat, Rat and Guinea-pig

应用“离体肠道流体推进检测系统”发现:(1)大鼠十二指肠的腔内压较高,并循空肠—回肠—结肠逐渐降低。(2)豚鼠、大鼠、猫十二指肠、空肠的推进活动不活跃,回肠自发明显而规律的推进复合波,结肠的袋状壁运动及推进复合波强劲,并有显著的肛向纯输出。(3)三种不同食性动物离体小肠的推进复合波频率在大鼠最快,豚鼠次之,猫最慢;但大鼠和豚鼠的推进波频率曲线在结肠交叉倒置,转变为豚鼠(草食)—大鼠(杂食)—猫(肉食)的频率高低次序。(4)豚鼠空肠、回肠推进复合波幅值高于大鼠;在豚鼠结肠,推进波的肛向幅值更明显升高,致使肛向纯输出远超过大鼠。(5)实验动物肠管的紧张性及腔内压高低循远口方向形成梯度,且不同食性动物肠道的壁运动和推进行为各具特点,以适应不同类型食物消化吸收、残渣传送、粪团形成和排出的功能需要;这是肠平滑肌和壁内神经调控机制适应性发展的结果。

By Using 'The System for Detecting Fluid Propulsion of Isolated Intestinal Segment,' it is fourd that propulsion of duodenum and jejunum from cat, rat and guinea-pig are unactive; ileum initiates significant propulsive complex; colon arises baggy wall movement, and its propulsive complexes are powerful and with significant net aboral fluid propulsion. It is also found that with diffirent diets, the behaviour of intestinal propulsion of these 3 kinds of animal are different. These are the results of adaptable devolopment of meeting functions of smooth muscle and enteric nervous system for food digestion and absorption and for transfer of remnants.