非小细胞肺癌中C-myc蛋白表达及意义
被引量:2
Significance of C-myc Expression in NSCLC
摘要
为探讨 C-myc蛋白在非小细胞肺癌组织中的表达及临床意义 ,采用免疫组化二步法 ,检测了非小细胞肺癌组织 40例中 C-myc蛋白的表达。结果显示 ,C-myc蛋白表达上调可能与肺癌的发生有关 。
出处
《数理医药学杂志》
2003年第2期120-121,共2页
Journal of Mathematical Medicine
基金
国家自然科学基金资助项目 ( 3 9870 3 0 5 )
参考文献1
-
1姜泊 主编.细胞基础凋亡与临床:第1版[M].北京:人民军医出版社,1999.25-30.
同被引文献21
-
1Qing Wang~1 Zhi Ying Lin~2 Xiao Li Feng~3 ~1Department of Microbiology,Medical Center of Fudan University.the former Shanghai Medical University,Shanghai 200032,China ~2Liver Cancer Institute,Zhongshan Hospital,Shanghai 200032,China ~3Shanghai Institute of Biochemistry,Academy Sinica,Shanghai 200031,ChinaQing Wang earned master degree from Shanghai Medical University in 1996,now a senior lecturer of microbiology,specialized in the role of oncogcncs on tumor metastasis,having 8 papers published..Alterations in metastatic properties of hepatocellular carcinoma cell following H-ras oncogene transfection[J].World Journal of Gastroenterology,2001,7(3):335-339. 被引量:48
-
2Pei L, Melmed S. Isolation and characterization of a Pituitary tumor-transforming geng (PTTG) [J]. Mol Endocrinol, 1997, 11: 433.
-
3Dominguez A, Ramos-Morales F, Romero F, et al. hPTTG, a human homologue of rat PTTG, is overexpressed in hematopoietic neoplasms. Evidence for a transcriptional activation function of hPTTG [J]. Oncogene,1998,17 :2187.
-
4Zhang X, Horwitz GA, Prezant TR, et al. Structure, expression, and function of human pituitary tumor-transforming geng (PTTG)[J]. Mol Endocrinol, 1999, 13: 156.
-
5Prezant TR, Kadioglu P, Melmed S. An intronless homolog human proto-oncogene hPTTG is expressed in pituitary tumors: evidence for hPTTG family[J]. J Clin Endocrinol Metab, 1999, 84: 1149.
-
6Chen L, Puri R, Kakar SS, et al. Identification of the human pituitary tumor transforming geng (hPTTG) family: molecular structure, expression, and chromosomal localization [J]. Gene, 2000, 248: 41.
-
7Strausberg RL, Dahl CA, Klausner RD .New opportunities for uncovering the molecular basis of cancer [J]. Nat Genet, 1997, 15: 415.
-
8Pei L. Activation of mitogen-activated protein kinase cascade regulates pituitary tumor-transforming gene trsnsactivation function [J]. J Biol Chem, 2000, 275: 31191.
-
9YU R, Heaney A, Lu W, et al. Pituitary tumor transforming gene (PTTG) causes aneuploidy and p53-dependent and p53-inpendent apoptosis[J]. J Biol Chem, 2000, 275: 36502.
-
10Heaney AP, Horwitz GA, Wang Z, et al. Early involvement of estrogen-induced pituitary tumor transforming gene and fibroblast growth factor expression in prolactinoma pathogenesis [J]. Nat Med, 1999, 5: 1317.
二级引证文献8
-
1韩煜雯,曾秋铭,李丽,杨莹莹,刘欢,林原.肝癌与C-myc的关系研究进展[J].临床肝胆病杂志,2008,24(2):153-155. 被引量:9
-
2万茜,章永红.中药诱导肺癌细胞凋亡的研究进展[J].河北中医,2009,31(4):628-630. 被引量:2
-
3南阳,韩磊,张安玲,浦佩玉,钟跃,康春生.miR-451对胶质瘤细胞株A172生物学特征的影响[J].中华神经外科杂志,2010,26(9):847-850. 被引量:6
-
4王爱云,樊贤超,陆茵,张伟伟,郑仕中.以中药诱导肿瘤休眠作为肿瘤防治策略的探讨[J].中草药,2011,42(3):598-601. 被引量:9
-
5陆乾人,周庆华,顾翔华,鲍玉芳,朱卫红,王晓军,房滢熙,厉娜.“促阴限阳”诱导肺癌细胞凋亡探析[J].上海中医药杂志,2011,45(6):12-15. 被引量:3
-
6沈丽萍,刘苓霜.中医药治疗肺癌机制研究进展[J].上海中医药杂志,2012,46(3):85-88. 被引量:1
-
7郭瑞珍,王娟,周开梅.皮肤病理性瘢痕上皮中Cx43和C-myc的表达及意义[J].中国皮肤性病学杂志,2013,27(1):19-22. 被引量:7
-
8朱赛君,许尤琪.中药复方治疗肺癌作用机理的实验研究进展[J].中医药导报,2018,24(12):57-61. 被引量:11
-
1邵馨,顾春燕.P27和skp2在肝细胞癌中的表达及其意义[J].临床肝胆病杂志,2009,25(2):120-121. 被引量:2
-
2李琦,李湘平,梁勇,刘雄.下咽癌中基质金属蛋白酶-2的表达及其临床意义[J].第一军医大学学报,2003,23(5):495-497. 被引量:2
-
3李道成,梁立治,王慧颖.Survivin蛋白在子宫内膜样腺癌中的表达及其临床意义[J].世界肿瘤杂志,2007,6(3):165-167.
-
4罗明华,詹伏兰,蔡广玲,余光银,李冠武.缺氧诱导因子-1α、血管内皮生长因子与胃癌血管生成及转移生物学行为的关系[J].汕头大学医学院学报,2005,18(1):18-20. 被引量:8
-
5张艳英,左磊,吕娜娜,张本华,常金,刘文健.S100A4蛋白在食管鳞癌组织中的表达[J].肿瘤基础与临床,2011,24(5):385-387.
-
6刘兰华.β-Catenin在宫颈上皮内瘤样变及宫颈鳞癌中的表达及意义[J].长江大学学报(自然科学版),2011,8(2):137-139. 被引量:2
-
7陆雪明,王树钦,林松青.C-erbB-2蛋白在贲门癌中的表达及其与预后的关系[J].中国肿瘤外科杂志,2014,6(2):103-105. 被引量:1
-
8黄力,杨勇,姚启盛,王晓康,陈从波.膀胱移行细胞癌中survivin基因和血管内皮生长因子的表达和意义[J].现代肿瘤医学,2009,17(12):2371-2373. 被引量:2
-
9李琦,李湘平,姚连生.nm23基因在下咽癌中的表达及其意义[J].广东医学,2002,23(7):683-684.
-
10耿海燕,邵淑丽.Survivin和p53蛋白在卵巢上皮性肿瘤中的表达、相关性及意义[J].中国现代药物应用,2010,4(3):8-9. 被引量:4