经皮测定新生儿胆红素临床应用探讨

Exploration of Clinical Application cf Transcuteneous Bilirubinometer in Newbrn

经皮测定1～16天正常新生儿122例及1～15天患婴26例的胆红素。并与经静脉取血应用咖啡因法测血清总胆红素浓度进行对比。结果发现,正常新生儿和患婴TcB读数均以额部为最高,TcB读数与血清胆红素二者间呈线性正相关(P<0.001)。经皮测TcB读数后查线性相关图,即得知相应的血清总胆红素浓度,可对新生儿高胆红素血症进行早期筛查及监测,及时指导临床治疗。

Transcuteneous use of jaundice 101 to determine 122 cases of normal newborn, aged 1～～16 days and 26 patients of 1-15 days were reported. At the sametime compare the value with the blood total serum bilirubin concentration taking from venous blood by 'Caffine Method'. Five surface regions were examined in each case:forehead, middle of sternum, right upper abdomen, right knee and right sole. In the normal 122 casss of newborn the TcB values were 16.11, 15.89,13.20,12.02 and 9.94. The TcB value is highest in the forehead both in normal new borns and patients. To compare the forehead and sternum P> 0.05, forehead to right upper abdomen, knee and sole P<0.01 and P<0.05 TcB value and serum bilirubinreveled positive linear relationship. In normal greup r=0.9246, while in patientr=0.9562, P are all<0.001. From the TcB value on linear relationship figure, it. can promptly get out the corresponding total serumabilirubin concentration. TcB is a non-invasive simple technique, used as a screening method in early diagnosis of hyperbilirubinemia in newborn. It is quite accurate and variation in bilirubin values can be observed promptly and as wel can direct clinical treatment.