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花椒治疗疥疮的实验及临床研究 被引量:2

The Clinical and Laboratory Studies on Scabicide Activity of Zanthoxylum
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摘要 较系统地研究芸香科植物花椒对疥疮的治疗作用。杀螨实验证实花椒的氯仿提取物(ZTE)对疥螨具有较强的触杀作用,触杀8h的半数致死量为9.311791,且杀螨率与药物浓度及触杀时间呈正相关。动物实验证实ZTE对兔疥疮疗效显著。临床试用20%ZTE治疗55例疥疮病人,用药五次治愈率为74.55%,未见毒副作用。 We had studied ths scabicide effect of zanthoxylum systematically. It was demonstrated that zanthoxylum trichlormethane extracts(ZTE) had strong scabicide activity in animal experiment. The results were dealed with by computer. The LD50 of ZTE contacting with Sarcoptes scabiei in 8 hours was 9.311791,and the scabicide rate of ZTE was highly corelated with its concentration and contact time. ZTE treated scabious rabbit succesfully. 55 scabies patients were treated with 20% ZTE, the cure rate was 74.55% with five times application. No toxic and side effects were observed.
出处 《贵阳医学院学报》 CAS 1992年第4期255-258,共4页 Journal of Guiyang Medical College
关键词 疥疮 花椒 中医药疗法 螨病 scabis mites plant extracts zanthoxylum
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