集成毛细管电泳芯片的设计

Design of integrated capillary electrophoresis chip

利用ANSYS软件对集成毛细管电泳芯片微沟道内样品流动情况进行模拟,获得了不同进样模式下微沟道的结构与流体流速之间的关系,并以此为依据对芯片整体结构参数进行设计:毛细管沟道最终尺寸为宽度16μm,深度10μm,有效分离长度为3.5cm的圆角转弯形沟道,从而确定整个芯片设计。

?The fluid distribution in the microchannel of ICEC (Integrated Capillary Electrophoresis Chip) was simulated using ANSYS software.The relations between the microchannel structure and flow velocity under different sample injection modes were obtained.Then the optimized channel structure was chosen by the width of 16?μm,the depth of the chip was determined 10?μm and the effective dividing length of 3.5?cm with round corner channel.The chip structure was designed.