1Lang FF,Yung WK,Sawaya R.Adenovirus-mediated p53 gene therapy for human gliomas[J].Neurosurgery,1999,45(5):1093-1104.
2Schiebe M,Ohneseit P,Hoffmann W,et al.Analysis of mdm2 and p53 gene alterations in glioblastomas and its correlation with clinical factors[J].J Neurooncol,2000,49(3):197-203.
3Iwadata Y,Fujimoto S,Tagawa M,et al.Association of p53 gene mutation with decreased chemosensitivity in human malignant gliomas[J].Int J Cancer,1996,69(3):236-240.
4Chin KV,Ueda K,Pastan I,et al.Modulation of activity of the promoter of the human MDR1 gene by ras and p53[J].Science,1992,255(5043):459-462.
5Xu GW,Nutt CL,Zlatescu MC,et al.Inactivation of p53 sensitizes U87MG glioma cells to 1,3-bis(2-chlorothy1)-1-nitrosoutea[J].Cancer Res,2001,61(10):4155-4159.
6Shinoura N,Sakurai S,Asai A,et al.Caspase-9 transduction overrides the resistance mechanism against p53-mediated apoptosis in U87MG glioma cells[J].Neurosurgery,2001,49(1):177-186.
7Cerrato JA,Yung WK,Liu TJ.Introduction of mutant p53 into a wild-type p53-expressing glioma cell line confers sensitivity to Ad-p53-induced apoptosis[J].Neuro Oncol,2001,3(2):113-122.
8Kaghad M,Bonnet H,Yang A,et al.Monoallelically expressed gene related to p53 at 1p36,a region frequently deleted in neuroblastoma and other human cnancers[J].Cell,1997,90(4):809-819.
9Alonso ME,Bells MJ,Lomas J,et al.Absence of mutation of the p73 gene in astrocytic neoplasmas[J].Int J Oncol,2001,19(3):609-612.
10Shinoura N,Muramatsu Y,Asai A,et al.Degree of apoptosis induced by adenovirusmediated transduction of p53 or p73 alpha depends on the p53 status of glioma cells[J].Cancer Lett,2000,160(1):67-73.
3Clauss M, Sunderkottre C, Sveinbjornsson B, et al. A permissive role for tumor necrosis factor in vascular endothetial growth factor-induced vascular permeability[J]. Blood,2001,97(5) :1321.
4Soussi T. The P53 tumor suppressor gene: from molecular biology to clinical investigation[J]. Ann Ny Acad Sci,2000,9( 10):121 - 137.
