羟基磷灰石涂层的骨结合行为

Investigation on the Bonding Behavior of Hydroxyapatite Coating to Hard Tissue

使用等离子喷涂技术 ,在钛合金表面制备了羟基磷灰石涂层 .采用动物实验的方法 ,研究羟基磷灰石涂层的生物相容性 .生物力学实验结果表明 ,使用羟基磷灰石涂层 ,可以显著提高骨组织与种植体的界面结合强度 .扫描电镜观察显示 ,羟基磷灰石涂层与骨组织形成骨性结合 ,而钛合金种植体与骨组织之间存在纤维组织结构 .两种不同的界面结构 ,是导致种植体与骨组织结合强度差异的主要原因 .

Hydroxyapatite coating was applied to the surface of titanium alloy employing plasma spray technology. An animal model was employed to investigate the biocompatibility of the hydroxyapatite coating. It is revealed by push-out test that the hydroxyapatite coating greatly prompts the bonding strength between implant and surrounding hard tissues. SEM observation shows that a biological fixation is created between bone and hydroxyapatite, while a layer of fiber is formed between non-coated titanium implant and surrounding bone. The different interfacial fixation is the main factor, which causes great difference in interfacial strength.