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PGF_(2α)治疗青光眼的特点 被引量:3

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摘要 PGF2α是一种较为新型的抗青光眼药物 ,其降眼压作用系通过提高葡萄膜巩膜途径而非经典的小梁网途径的房水引流来实现 ,因此与以往抗青光眼药物特性有所不同 ,同时由于前列腺素可诱发炎性反应 ,因此也需要更严密的观察与应用。本文就其应用特性作一综述 ,以期为临床应用提供参考。
作者 王小兵
出处 《国外医学(眼科学分册)》 2003年第1期1-2,共2页 Foreign Medical Sciences(Section of Ophthalmology )
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参考文献10

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同被引文献28

  • 1王小兵,张海燕,李卫红,刘爱珍,曾衍钧.体外培养人眼睫状肌细胞的流体阻力定性观察[J].医用生物力学,2007,22(2):177-180. 被引量:1
  • 2Husain S,Crosson CE. Role of PKCepsilon in PGF2alpha-stimulated MMP-2 secretion from human ciliary muscle cells [ J ]. J Ocul Pharmacol Ther 2008 ;24 ( 3 ) :258-277.
  • 3Husain S, Jafri F, Crosson CE. Acute effects of PGF2alpha on MMP-2 secretion from human ciliary muscle cells:a PKC- and ERK-dependent process[J]. Invest Ophthalmol Vis Sci 2005 ;46 (5) :1706-1713.
  • 4Yousufzai SYK, Ye Z, Abdel-latif AA. Prostaglandin F2α and its analogs induce release of endogenous prostaglandins in iris and ciliary muscles isolated from cat and other mammalian species [J]. Exp Eye Res 1996;63(3) :305-310.
  • 5Yamaji K, Yoshitomi T, Ishikawa H, Usui S. Prostaglandins E1 and E2, but not F2alpha or latanoprost, inhibit monkey ciliary muscle contraction [ J ]. Curt Eye Res 2005 ; 30 ( 8 ) :561-555.
  • 6Miyake K, Ota I, Maekubo K, Ichihashi S, MiyakeS. Latanoprost accelerates disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema in early postoperative pseudophakias [ J]. Arch Ophthalmol 1999; 117 ( 1 ) :34-40.
  • 7Weinreb RN,Kim DM,Lindsey JD. Propagation of ciliary smooth muscle cells in vitro and effects of prostaglandin F2α on calcium effiux[ J]. Invest Ophthalmol Vis Sci 1992;33 (9) :2679- 2686.
  • 8Chen W,Andom T,Bhattacherjee P,Paterson C. Intracellular calcium mobilization following prostaglandin receptor activation in human ciliary muscle cells[ J ].Curr Eye Res 1997 ; 16 ( 8 ) :847- 853.
  • 9Shimura M, Yasuda K, Nakzawa T, Kashiwagi K. The effect of unoprostone isopropyl on Ca^2+ release-activated Ca^2+ currents in cultured monkey trabecular meshwork cells and ciliary muscle cells[ J]. J Ocul Pharmacol Ther 2006 ;22 (4) :219-226.
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