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治疗性疫苗研究进展 被引量:3

The Advances on Therapeutic Vaccination
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摘要 治疗性疫苗通过打破机体的免疫耐受 ,提高机体的特异性免疫反应 ,对一些目前尚无有效治疗药物的传染性疾病、肿瘤等起到治疗作用。介绍了治疗性疫苗的概况、机理和临床最新进展。 Therapeutic Vaccination is an efficient new technique on treatment of chronic infection disease and tumor by breaking up immunological tolerance and stimulating specific immune response. And it would be therapeutic procedure with the lowest cost and the potentially greatest benefit. This article introduce the general situation,mechanism and clinical trials of therapeutic vaccine. ;
出处 《中国生物工程杂志》 CAS CSCD 2003年第2期83-85,90,共4页 China Biotechnology
关键词 治疗性疫苗 研究进展 特异性免疫反应 免疫治疗 Therapeutic Vaccine Specific immune response Immunotherapy
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参考文献14

  • 1[1]Krug LM,Grant SC,Miller VA,et al.Strategies to eradicate minimal residual disease in cell lung cancer:high-dose chemotherapy with autologous bone marrow transplantation,matrix metalloproteinase inhibitors,andBEC2 plus BCG vaccination. Semin Oncol,1999,26:55~61
  • 2[2]Kozlowski J.This month in investigative urology:Immunotherapy of bladder cancer.J.Urol,1999 .162(5):1806~1811
  • 3[3]Agarwala SS,Kirkwood JM.Adjuvant therapy of melamona.Semin Surg Oncol,1998,14:302~310
  • 4[4]Goebel FD,Mannhalter JW,Belshe RB,et al.Recombiant gp160as a therapeuticvaccine for HIV-infection:result of a large randomized,controlled trial.European Multinational IMMUNO AIDS Vaccine Study Group.AIDS,1999,13:1461~1468
  • 5[5]Amara RR,Villinger F .Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine.Science,2001,292:69~74
  • 6[6]Celis E,Chang TS .HbsAg-serum protein complexes stimulate immune T lymphocytes more efficiently than do pure HbsAg.Hepatology,1984,6:.1116~1121
  • 7[7]Ishioka GY,Fikes J,Hermanson G,et al.Utilization of MHC classⅠtransgenicmice for development of minigene DNA vaccines encoding multiple HLA-restrictedCTL epitopes.J Immunol 1999,162(7):3915~3925
  • 8[8]Ayed M,Ben Hassine L,Ben Slama R,et al.Results ofBCG in the treatment ofpTa and pT1 bladder tumors:Evaluation of a long protocol using 75 mg of Pasteurstrain BCG.Prog Urol,1998 ,8:206~210
  • 9郭焱,金宁一,张应玖,夏志平,王宏伟,郭志儒,罗晶,殷震.EHV-1_(CN)与IL-2基因共表达核酸疫苗诱导产生CTL的观察[J].中国生物制品学杂志,2001,14(2):81-83. 被引量:2
  • 10[10]Sabbaj S,Mulligan MJ.Cytokine profiles in seronegative volunteers immunized with a recombinant canarypox and gp120 prime-boost HIV-1 vaccine.AIDS ,2000 ,14 (10):1365~1374

二级参考文献3

  • 1Kim J J,J Interferon Cytokine Res,1999年,19卷,1期,77页
  • 2Sin K Q,Vaccine,1999年,17卷,858页
  • 3金冬雁(译),分子克隆实验指南,1993年,16页

共引文献1

同被引文献22

  • 1刘景利,孙建宏,管雪婷,王杰.治疗性疫苗研究进展[J].畜牧兽医科技信息,2005,21(10):12-13. 被引量:2
  • 2闫东梅,朱迅.治疗性疫苗的发展现状与应用前景[J].中国生物制品学杂志,2005,18(6):535-537. 被引量:3
  • 3Krug L M, Grant S C, Miller V A, et al. Strategies to eradicate minimal residual disease in cell lung cancer:high dose chemotherapy with autologous bone marrow transplantation, mat rix metalloproteinase inhibitors, and BEC2 plus BCG vaccination[J]. Semin Oncol, 2009, 26:56-61.
  • 4Kozlowski J. This month in investigative urology: Immunotherapy of bladder cancer[J].Int J Urol,2005,162(5):1806-1811.
  • 5Agarwala S S, Kirkwood J M. Adjuvant therapy of melamona[J]. Semin Surg Oncol, 2003,14:302-310.
  • 6Goebel F D, Mannhaher J W, Belshe R B, et al. Recombiant gpl60 as a therapeutic vaccine for HIV-infection:resuh of a large randomized, controlled trial [J]. European Multinational IMMUNO AIDS Vaccine Study Group,2005,13:1461-1468.
  • 7Amara R R, Villinger F. Control of a mucosal challenge and prevention of AIDS by a muhiprotein DNA/MVA vaccine [J]. Science,2001,292:69-74.
  • 8Celis E, Chang T S. HbsAg serum protein complexes stimulate immune T lymphocytes more efficiently than do pure HbsAg[J]. Hepatology,2004,6:1116-1121.
  • 9Ishioka G Y, Fikes J, Hermanson G, et al .Utilization of MHC class transgenic mice for development of minigene DNA vaccines encoding multiple HLA-restricted CTL epitopes [J]. J Immunol,2008,162(7):3915-3925.
  • 10Ayed M, Ben Hassine L, Ben Slama R, et al. Results of BCG in the treatment of Taandp Tlbl addertumors: Evaluation of alone protocol using 75 mg of Pasteurstrain BCG [J]. Prog Urol, 2005,8:206-210.

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