高压氧加放疗联合治疗鼻咽癌临床疗效分析

Effects of Radiation Combined with Hyperbaric Oxygenation for Nasopharyngeal Carcinoma

目的探讨高压氧加放射治疗鼻咽癌的治疗效果。方法42例病理确诊的鼻咽癌患者,22例接受高压氧加放射治疗的综合治疗。20例接受单纯放射治疗。对颈部预防性照射。结果 5 a生存率为57.1％,高压氧加放射治疗为63.5％,明显高于单纯放射治疗40.0％(P<0.05)。颈部总淋巴结转移率为80.9％(34/42),放射治疗加高压氧能较好控制颈部转移灶。结论综合治疗较单纯放射治疗疗效好。

Objective To evaluate the efficiency of hyperbaric oxygenation plus radiotherapy for nasopharyngeal carcinoma. Methods 42 patients with nasopharyngeal carcinoma proved topathologically were reviewed.22 patients received hyperbaric oxygenation plus radiation therapy and 20 patients received radiation therapy alone.Results The overall 5-year survival of all the patients was 52.4% ,the 5-year survival of the patients with combined treatment was significantly higher than that of radiotherapy alone(63 .6% vs 40.0% ), ( P < 0.05 ) . The transport rate of neck lymph gland was 80.9 % (34/42) . Patients had cervical lymph node metastasis at presentation, and all of them were controlled by radiotherapy. Conclusions The result of combined treatment was better than that of radiotherapy alone.