H型高血压与急性心肌梗死患者急诊经皮冠状动脉介入治疗术后发生慢血流的相关性

Association Between H-type Hypertension and Slow Flow Phenomenon in Patients Undergoing PCI Therapy with Acute Myocardial Infarction

目的探讨H型高血压与ST段抬高型心肌梗死(STEMI)患者接受急诊经皮冠状动脉介入治疗(PCI)术后冠状动脉慢血流(CSF)发生的关系。方法选取我院2013年1月至2014年7月收治的120例首次发生STEMI伴有高血压并接受急诊PCI术治疗的患者为研究对象,所有入选者均符合该研究入选标准。根据术中是否出现慢血流分为慢血流组(27例)和非慢血流组(93例),并测定两组患者血脂、血高敏C反应蛋白(hs-CRP)及血同型半胱氨酸(Hcy)等指标水平。比较慢血流组与非慢血流组H型高血压(Hcy≥10μmol/L)患者比例及hs-CRP水平;应用Logistic回归分析法筛选慢血流的危险因素。结果慢血流组H型高血压患者比例显著高于非慢血流组(P<0.05);Logistic回归分析显示,H型高血压是慢血流的相关危险因素。结论 H型高血压与STEMI患者行急诊PCI术后慢血流的发生可能相关。

Aim To study the association between H-type hypertension and coronary slow flow( CSF) in patients undergoing PCI therapy with acute myocardial infarction. Methods 120 patients with hypertension and acute myocardial infarction which accepted the emergency treatment of PCI in our hospital from January 2013 to July 2014 were enrolled as the research subjects. According to the blood flow level presented during the PCI therapy,these cases were divided into CSF group( 27 cases) and non-CSF group( 93 cases). Blood lipid level,high sensitivity C-reactive protein( hs-CRP)and plasma homocysteine were tested and compared between the two groups,so did the proportion of patients with H-type hypertension. The risk factors of CSF were screened by Logistic regression analysis. Results In CSF group,the proportion of patients with H-type hypertension was significantly higher than that in non-CSF group( P < 0. 05). With Logistic regression analysis,H-type hypertension was found to be a significant risk factor of CSF. Conclusion H-type hypertension is closely related to the CSF in patients with acute myocardial infarction which undergo primary PCI treatment.