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非甾体类消炎药抗肝癌作用研究进展 被引量:2

The roles of NSAID against liver neoplasm
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摘要 非甾体类消炎药抗肿瘤细胞增殖和诱导肿瘤细胞凋亡的作用已引起广泛关注 ,尤其是抗肝癌方面已成为研究热点。肝细胞癌中COX 2的表达与癌细胞的分化程度、转移、预后相关。其抗肿瘤的作用机制可能与抑癌基因失活、改变某些与增殖及凋亡有关基因表达、影响免疫、促进肿瘤血管生成有关。现综述特异性COX 2抑制剂抗肝癌作用机制及临床应用。
作者 杨震
出处 《国外医学(肿瘤学分册)》 2003年第1期51-54,共4页 Foreign Medical Sciences (Cancer Section)
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